Research & Development Programs
Jerini is a leader in the systematic discovery and development of peptidomimetic and small molecule drugs derived from peptides.The company's Peptides-to-Drugs (P2D) technology platform facilitates the development of both peptidomimetic drugs (injectable), and small molecules (orally available) depending on the disease indication. Systematic program diversification balances the inherent risks and benefits associated with drug development and ensures significant opportunities for Jerini's future growth and increased company value.
| Target (Compound) | Partner | Indication | Discovery | Preclinical | Phase I | Phase II | Phase III | Submisson |
|---|---|---|---|---|---|---|---|---|
| Bradykinin B2R (Icatibant) | Hereditary Angioedema Hereditary angioedema | |||||||
| Bradykinin B2R (Icatibant) | Drug-Induced Angioedema* | |||||||
| Bradykinin B2R (Icatibant) | Capillary Leak Syndrome** | |||||||
| Bradykinin B2R (JSM-10292) | Pain / Inflammation | |||||||
| C5aR (JSM-1375) | Ophthalmology*** | |||||||
| C5aR (JSM-7717) | Inflammation | |||||||
| α5ß1 Integrin (JSM 6427) | Ophthalmology*** | |||||||
| α5ß1 Integrin (JSM-8757 | Oncology | |||||||
| Bradykinin B1R (undisclosed) | Pain / Inflammation | |||||||
| Undisclosed | Alcon | Ophthalmology | ||||||
| Undisclosed (Multiple Targets) | Baxter | Hemophilia |


